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Target5-hydroxytryptamine receptor 1A (5HT1A)
LigandBDBM50054708
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1061
IC50 5.8±n/a nM
Citation Norman, MHNavas, FThompson, JBRigdon, GC Synthesis and evaluation of heterocyclic carboxamides as potential antipsychotic agents. J Med Chem39:4692-703 (1997) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
5-hydroxytryptamine receptor 1A (5HT1A)
Name:Serotonin 1a (5-HT1a) receptor
Synonyms:5-HT1A | 5-hydroxytryptamine receptor 1A | Serotonin 1a (5-HT1a) receptor
Type:Enzyme
Mol. Mass.:46192.09
Organism:Mus musculus (Mouse)
Description:Q64264
Residue:421
Sequence:
MDMFSLGQGNNTTTSLEPFGTGGNDTGLSNVTFSYQVITSLLLGTLIFCAVLGNACVVAA
IALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCC
TSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPED
RSNPNECTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKKGAGT
SFGTSSAPPPKKSLNGQPGSGDCRRSAENRAVGTPCANGAVRQGEDDATLEVIEVHRVGN
SKGHLPLPSESGATSYVPACLERKNERTAEAKRKMALARERKTVKTLGIIMGTFILCWLP
FFIVALVLPFCESSCHMPELLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFC
R
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BDBM50054708
NameBDBM50054708
Synonyms:1H-Indole-3-carboxylic acid [4-(4-benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-amide | CHEMBL142456
TypeSmall organic molecule
Emp. Form.C24H27N5OS
Mol. Mass.433.569
SMILESO=C(NCCCCN1CCN(CC1)c1nsc2ccccc12)c1c[nH]c2ccccc12
Structure
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n/a