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TargetPPYR1
LigandBDBM50060731
Substrate/Competitorn/a
Meas. Tech.ChEMBL_143981
Ki>10000±n/a nM
Citation Hipskind, PALobb, KLNixon, JABritton, TCBruns, RFCatlow, JDieckman-McGinty, DKGackenheimer, SLGitter, BDIyengar, SSchober, DASimmons, RMSwanson, SZarrinmayeh, HZimmerman, DMGehlert, DR Potent and selective 1,2,3-trisubstituted indole NPY Y-1 antagonists. J Med Chem40:3712-4 (1997) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
PPYR1
Name:Neuropeptide Y receptor type 4
Synonyms:NPY-Y4 | NPY4-R | Neuropeptide Y receptor type 4 | PP1 | Pancreatic polypeptide receptor 1
Type:Enzyme Catalytic Domain
Mol. Mass.:42207.58
Organism:Homo sapiens (Human)
Description:NPY-Y4 PPYR1 HUMAN::P50391
Residue:375
Sequence:
MNTSHLLALLLPKSPQGENRSKPLGTPYNFSEHCQDSVDVMVFIVTSYSIETVVGVLGNL
CLMCVTVRQKEKANVTNLLIANLAFSDFLMCLLCQPLTAVYTIMDYWIFGETLCKMSAFI
QCMSVTVSILSLVLVALERHQLIINPTGWKPSISQAYLGIVLIWVIACVLSLPFLANSIL
ENVFHKNHSKALEFLADKVVCTESWPLAHHRTIYTTFLLLFQYCLPLGFILVCYARIYRR
LQRQGRVFHKGTYSLRAGHMKQVNVVLVVMVVAFAVLWLPLHVFNSLEDWHHEAIPICHG
NLIFLVCHLLAMASTCVNPFIYGFLNTNFKKEIKALVLTCQQSAPLEESEHLPLSTVHTE
VSKGSLRLSGRSNPI
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50060731
NameBDBM50060731
Synonyms:2-(2,4-Dichloro-phenoxymethyl)-1-methyl-3-piperidin-1-ylmethyl-1H-indole | CHEMBL123410
TypeSmall organic molecule
Emp. Form.C22H24Cl2N2O
Mol. Mass.403.345
SMILESCn1c(COc2ccc(Cl)cc2Cl)c(CN2CCCCC2)c2ccccc12
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a