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Target
Neuropeptide Y receptor type 5
Ligand
BDBM50060731
Substrate
n/a
Meas. Tech.
ChEMBL_144126 (CHEMBL750099)
Ki
>10000±n/a nM
Citation
 Hipskind, PA; Lobb, KL; Nixon, JA; Britton, TC; Bruns, RF; Catlow, J; Dieckman-McGinty, DK; Gackenheimer, SL; Gitter, BD; Iyengar, S; Schober, DA; Simmons, RM; Swanson, S; Zarrinmayeh, H; Zimmerman, DM; Gehlert, DR Potent and selective 1,2,3-trisubstituted indole NPY Y-1 antagonists. J Med Chem 40:3712-4 (1997) [PubMed]  Article 
Target
Name:
Neuropeptide Y receptor type 5
Synonyms:
NPY-Y5 | NPY-Y5 receptor | NPY5-R | NPY5R | NPY5R_HUMAN | NPYR5 | NPYY5 | Neuropeptide Y receptor type 5 | Neuropeptide Y receptor type 5 ( NPY Y5) | Y5 receptor
Type:
Enzyme
Mol. Mass.:
50746.64
Organism:
Homo sapiens (Human)
Description:
Q15761
Residue:
445
Sequence:
MDLELDEYYNKTLATENNTAATRNSDFPVWDDYKSSVDDLQYFLIGLYTFVSLLGFMGNLLILMALMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKVMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSLVELQETFGSALLSSRYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISCGLSNKENRLEENEMINLTLHPSKKSGPQVKLSGSHKWSYSFIKKHRRRYSKKTACVLPAPERPSQENHSRILPENFGSVRSQLSSSSKFIPGVPTCFEIKPEENSDVHELRVKRSVTRIKKRSRSVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCLNPILYGFLNNGIKADLVSLIHCLHM
  
Inhibitor
Name:
BDBM50060731
Synonyms:
2-(2,4-Dichloro-phenoxymethyl)-1-methyl-3-piperidin-1-ylmethyl-1H-indole | CHEMBL123410
Type:
Small organic molecule
Emp. Form.:
C22H24Cl2N2O
Mol. Mass.:
403.345
SMILES:
Cn1c(COc2ccc(Cl)cc2Cl)c(CN2CCCCC2)c2ccccc12
Structure:
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