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Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM50063800
Substrate
n/a
Meas. Tech.
ChEMBL_200983 (CHEMBL801236)
Ki
0.6±n/a nM
Citation
 Ucar, H; Van derpoorten, K; Cacciaguerra, S; Spampinato, S; Stables, JP; Depovere, P; Isa, M; Masereel, B; Delarge, J; Poupaert, JH Synthesis and anticonvulsant activity of 2(3H)-benzoxazolone and 2(3H)-benzothiazolone derivatives. J Med Chem 41:1138-45 (1998) [PubMed]  Article 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25124.85
Organism:
Homo sapiens (Human)
Description:
Q99720
Residue:
223
Sequence:
MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSRLIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRYWAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
  
Inhibitor
Name:
BDBM50063800
Synonyms:
3-(2-Piperidin-1-yl-ethyl)-6-propyl-3H-benzothiazol-2-one | CHEMBL274699
Type:
Small organic molecule
Emp. Form.:
C17H24N2OS
Mol. Mass.:
304.45
SMILES:
CCCc1ccc2n(CCN3CCCCC3)c(=O)sc2c1
Structure:
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