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Target
Beta-2 adrenergic receptor
Ligand
BDBM50064220
Substrate
n/a
Meas. Tech.
ChEMBL_38607 (CHEMBL652290)
IC50
>10000±n/a nM
Citation
 Blanc, M; Tamir, A; Aubriot, S; Michel, MC; Bouzoubaa, M; Leclerc, G; Demenge, P Synthesis and adrenergic activity of a new series of N-aryl dicyclopropyl ketone oxime ethers: SAR and stereochemical aspects. J Med Chem 41:1613-8 (1998) [PubMed]  Article 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2 | ADRB2_CANLF
Type:
PROTEIN
Mol. Mass.:
46593.67
Organism:
Canis familiaris
Description:
ChEMBL_56504
Residue:
415
Sequence:
MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL
  
Inhibitor
Name:
BDBM50064220
Synonyms:
CHEMBL42267 | Dicyclopropyl-methanone O-{2-hydroxy-3-[4-(2-methyl-2-nitro-propyl)-phenylamino]-propyl}-oxime
Type:
Small organic molecule
Emp. Form.:
C20H29N3O4
Mol. Mass.:
375.462
SMILES:
CC(C)(Cc1ccc(NCC(O)CO[N-][C+](C2CC2)C2CC2)cc1)[N+]([O-])=O
Structure:
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