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Target
Genome polyprotein
Ligand
BDBM50065900
Substrate
n/a
Meas. Tech.
ChEMBL_158967 (CHEMBL766325)
IC50
8700±n/a nM
Citation
 Yoakim, C; Ogilvie, WW; Cameron, DR; Chabot, C; Guse, I; Haché, B; Naud, J; O'Meara, JA; Plante, R; Déziel, R beta-Lactam derivatives as inhibitors of human cytomegalovirus protease. J Med Chem 41:2882-91 (1998) [PubMed]  Article 
Target
Name:
Genome polyprotein
Synonyms:
Human rhinovirus A protease | Human rhinovirus B 3A protease
Type:
PROTEIN
Mol. Mass.:
44361.04
Organism:
Human rhinovirus B
Description:
ChEMBL_158953
Residue:
401
Sequence:
AFRPCNVNTKIGNAKCCPFVCGKAVTFKDRSTCSTYNLSSSLHHILEEDKRRRQVVDVMSAIFQGPISLDAPPPPAIADLLQSVRTPRVIKYCQIIMGHPAECQVERDLNIANSIIAIIANIISIAGIIFVIYKLFCSLQGPYSGEPKPKTKVPERRVVAQGPEEEFGRSILKNNTCVITTGNGKFTGLGIHDRILIIPTHADPGREVQVNGVHTKVLDSYDLYNRDGVKLEITVIQLDRNEKFRDIRKYIPETEDDYPECNLALSANQDEPTIIKVGDVVSYGNILLSGNQTARMLKYNYPTKSGYCGGVLYKIGQILGIHVGGNGRDGFSAMLLRSYFTGQIKVNKHATECGLPDIQTIHTPSKTKLQPSVFYDVFPGSKEPAVLTDNDPRLEVNFKEA
  
Inhibitor
Name:
BDBM50065900
Synonyms:
(S)-2-Benzyl-4-oxo-azetidine-1-carboxylic acid methyl-(4-trifluoromethanesulfinyl-benzyl)-amide | CHEMBL95515
Type:
Small organic molecule
Emp. Form.:
C20H19F3N2O3S
Mol. Mass.:
424.437
SMILES:
CN(Cc1ccc(cc1)S(=O)C(F)(F)F)C(=O)N1[C@@H](Cc2ccccc2)CC1=O
Structure:
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