Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50067087
Substrate
n/a
Meas. Tech.
ChEMBL_31999 (CHEMBL646596)
Ki
2300000±n/a nM
Citation
 van Muijlwijk-Koezen, JE; Timmerman, H; Link, R; van der Goot, H; IJzerman, AP A novel class of adenosine A3 receptor ligands. 1. 3-(2-Pyridinyl)isoquinoline derivatives. J Med Chem 41:3987-93 (1998) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50067087
Synonyms:
3,4-Dichloro-N-(3-pyridin-2-yl-isoquinolin-1-yl)-benzamidine | CHEMBL338501
Type:
Small organic molecule
Emp. Form.:
C21H14Cl2N4
Mol. Mass.:
393.269
SMILES:
NC(=Nc1nc(cc2ccccc12)-c1ccccn1)c1ccc(Cl)c(Cl)c1 |w:2.2|
Structure:
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