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Target
Dihydroxyacetone phosphate acyltransferase
Ligand
BDBM50068941
Substrate
n/a
Meas. Tech.
ChEBML_53904
IC50
>50000000±n/a nM
Citation
 Cox, RJ; Schouten, JA; Stentiford, RA; Wareing, KJ Peptide inhibitors of N-succinyl diaminopimelic acid aminotransferase (DAP-AT): a novel class of antimicrobial compounds. Bioorg Med Chem Lett 8:945-50 (1999) [PubMed]  Article 
Target
Name:
Dihydroxyacetone phosphate acyltransferase
Synonyms:
Acyl-CoA:dihydroxyacetonephosphateacyltransferase | DAPAT | DHAPAT | GNPAT | GNPAT_HUMAN
Type:
PROTEIN
Mol. Mass.:
77187.04
Organism:
Homo sapiens (Human)
Description:
ChEMBL_53899
Residue:
680
Sequence:
MESSSSSNSYFSVGPTSPSAVVLLYSKELKKWDEFEDILEERRHVSDLKFAMKCYTPLVYKGITPCKPIDIKCSVLNSEEIHYVIKQLSKESLQSVDVLREEVSEILDEMSHKLRLGAIRFCAFTLSKVFKQIFSKVCVNEEGIQKLQRAIQEHPVVLLPSHRSYIDFLMLSFLLYNYDLPVPVIAAGMDFLGMKMVGELLRMSGAFFMRRTFGGNKLYWAVFSEYVKTMLRNGYAPVEFFLEGTRSRSAKTLTPKFGLLNIVMEPFFKREVFDTYLVPISISYDKILEETLYVYELLGVPKPKESTTGLLKARKILSENFGSIHVYFGDPVSLRSLAAGRMSRSSYNLVPRYIPQKQSEDMHAFVTEVAYKMELLQIENMVLSPWTLIVAVLLQNRPSMDFDALVEKTLWLKGLTQAFGGFLIWPDNKPAEEVVPASILLHSNIASLVKDQVILKVDSGDSEVVDGLMLQHITLLMCSAYRNQLLNIFVRPSLVAVALQMTPGFRKEDVYSCFRFLRDVFADEFIFLPGNTLKDFEEGCYLLCKSEAIQVTTKDILVTEKGNTVLEFLVGLFKPFVESYQIICKYLLSEEEDHFSEEQYLAAVRKFTSQLLDQGTSQCYDVLSSDVQKNALAACVRLGVVEKKKINNNCIFNVNEPATTKLEEMLGCKTPIGKPATAKL
  
Inhibitor
Name:
BDBM50068941
Synonyms:
CHEMBL173513 | dilithium 2-[1-methylcarboxamido-2-phenyl-(1S)-ethylcarboxamido]-6-oxo-(2S)-heptanedioate
Type:
Small organic molecule
Emp. Form.:
C18H20N2O7
Mol. Mass.:
376.3617
SMILES:
CC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCC(=O)C([O-])=O)C([O-])=O
Structure:
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