Reaction Details Report a problem with these data
Target
Chymotrypsinogen B
Ligand
BDBM50070441
Substrate
n/a
Meas. Tech.
ChEBML_216648
IC50
>75000±n/a nM
Citation
 Déziel, R; Malenfant, E Inhibition of human cytomegalovirus protease N(o) with monocyclic beta-lactams. Bioorg Med Chem Lett 8:1437-42 (1999) [PubMed]  Article 
Target
Name:
Chymotrypsinogen B
Synonyms:
Beta-chymotrypsin | CTRB | CTRB1 | CTRB1_HUMAN | Chymotrypsin B chain A | Chymotrypsin B chain B | Chymotrypsin B chain C | Chymotrypsinogen B | Synonyms=CTRB
Type:
PROTEIN
Mol. Mass.:
27713.98
Organism:
Homo sapiens (Human)
Description:
ChEMBL_10909
Residue:
263
Sequence:
MASLWLLSCFSLVGAAFGCGVPAIHPVLSGLSRIVNGEDAVPGSWPWQVSLQDKTGFHFCGGSLISEDWVVTAAHCGVRTSDVVVAGEFDQGSDEENIQVLKIAKVFKNPKFSILTVNNDITLLKLATPARFSQTVSAVCLPSADDDFPAGTLCATTGWGKTKYNANKTPDKLQQAALPLLSNAECKKSWGRRITDVMICAGASGVSSCMGDSGGPLVCQKDGAWTLVGIVSWGSDTCSTSSPGVYARVTKLIPWVQKILAAN
  
Inhibitor
Name:
BDBM50070441
Synonyms:
2-Oxo-4-(pyridin-3-ylmethylsulfanyl)-azetidine-1-carboxylic acid ((R)-1-phenyl-ethyl)-amide | CHEMBL32171
Type:
Small organic molecule
Emp. Form.:
C18H19N3O2S
Mol. Mass.:
341.427
SMILES:
C[C@@H](NC(=O)N1C(CC1=O)SCc1cccnc1)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: