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TargetAdenosine deaminase
LigandBDBM50070643
Substrate/Competitorn/a
Meas. Tech.ChEBML_30791
Ki 1±n/a nM
Citation Curtis, MAVarkhedkar, VPragnacharyulu, PVAbushanab, E Adenosine deaminase inhibitors. Synthesis and biological evaluation of aralkyladenines (ARADS). Bioorg Med Chem Lett8:1639-42 (1999) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Adenosine deaminase
Name:Adenosine deaminase
Synonyms:ADA | Adenosine aminohydrolase
Type:Enzyme
Mol. Mass.:40910.44
Organism:Bos taurus (bovine)
Description:n/a
Residue:363
Sequence:
MAQTPAFNKPKVELHVHLDGAIKPETILYYGRKRGIALPADTPEELQNIIGMDKPLSLPE
FLAKFDYYMPAIAGCREAVKRIAYEFVEMKAKDGVVYVEVRYSPHLLANSKVEPIPWNQA
EGDLTPDEVVSLVNQGLQEGERDFGVKVRSILCCMRHQPSWSSEVVELCKKYREQTVVAI
DLAGDETIEGSSLFPGHVKAYAEAVKSGVHRTVHAGEVGSANVVKEAVDTLKTERLGHGY
HTLEDATLYNRLRQENMHFEVCPWSSYLTGAWKPDTEHPVVRFKNDQVNYSLNTDDPLIF
KSTLDTDYQMTKNEMGFTEEEFKRLNINAAKSSFLPEDEKKELLDLLYKAYGMPSPASAE
QCL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50070643
NameBDBM50070643
Synonyms:(2S,3R)-3-(6-Amino-purin-9-yl)-5-m-tolyl-pentan-2-ol | 3-(6-Amino-purin-9-yl)-5-m-tolyl-pentan-2-ol | CHEMBL418074
TypeSmall organic molecule
Emp. Form.C17H21N5O
Mol. Mass.311.3815
SMILESC[C@H](O)[C@@H](CCc1cccc(C)c1)n1cnc2c(N)ncnc12
Structure
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n/a