Reaction Details Report a problem with these data
Target
Beta-1,4-galactosyltransferase 1
Ligand
BDBM50072691
Substrate
n/a
Meas. Tech.
ChEBML_218108
Ki
1000000±n/a nM
Citation
 Chung, SJ; Takayama, S; Wong, CH Acceptor substrate-based selective inhibition of galactosyltransferases. Bioorg Med Chem Lett 8:3359-64 (1999) [PubMed]  Article 
Target
Name:
Beta-1,4-galactosyltransferase 1
Synonyms:
β-1,4-Galactosyltransferase I (β4GalT) | B4GALT1 | B4GT1_BOVIN | Beta-1,4-galactosyltransferase 1 | GALT | GGTB2
Type:
Enzyme
Mol. Mass.:
44860.74
Organism:
Bos taurus (Cattle)
Description:
P08037
Residue:
402
Sequence:
MKFREPLLGGSAAMPGASLQRACRLLVAVCALHLGVTLVYYLAGRDLRRLPQLVGVHPPLQGSSHGAAAIGQPSGELRLRGVAPPPPLQNSSKPRSRAPSNLDAYSHPGPGPGPGSNLTSAPVPSTTTRSLTACPEESPLLVGPMLIEFNIPVDLKLVEQQNPKVKLGGRYTPMDCISPHKVAIIIPFRNRQEHLKYWLYYLHPILQRQQLDYGIYVINQAGESMFNRAKLLNVGFKEALKDYDYNCFVFSDVDLIPMNDHNTYRCFSQPRHISVAMDKFGFSLPYVQYFGGVSALSKQQFLSINGFPNNYWGWGGEDDDIYNRLAFRGMSVSRPNAVIGKCRMIRHSRDKKNEPNPQRFDRIAHTKETMLSDGLNSLTYMVLEVQRYPLYTKITVDIGTPS
  
Inhibitor
Name:
BDBM50072691
Synonyms:
CHEMBL2303731 | N-[2-(3,5-Dihydroxy-2-hydroxymethyl-6-methoxy-tetrahydro-pyran-4-yloxy)-4,5-dihydroxy-6-mercaptomethyl-tetrahydro-pyran-3-yl]-acetamide
Type:
Small organic molecule
Emp. Form.:
C15H27NO10S
Mol. Mass.:
413.441
SMILES:
CO[C@@H]1O[C@@H](CO)[C@H](O)[C@H](O[C@@H]2O[C@@H](CS)[C@@H](O)[C@H](O)[C@@H]2NC(C)=O)[C@@H]1O |r|
Structure:
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