Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 1
Ligand
BDBM50073054
Substrate
n/a
Meas. Tech.
ChEMBL_143839 (CHEMBL747050)
IC50
39±n/a nM
Citation
 Kordik, CP; Reitz, AB Pharmacological treatment of obesity: therapeutic strategies. J Med Chem 42:181-201 (1999) [PubMed]  Article 
Target
Name:
Neuropeptide Y receptor type 1
Synonyms:
NPY-Y1 | NPY1-R | NPY1R | NPY1R_HUMAN | NPYR | NPYY1 | neuropeptide Y receptor Y1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44399.07
Organism:
Homo sapiens (Human)
Description:
NPY-Y1 NPY1R HUMAN::P25929
Residue:
384
Sequence:
MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASPVAFKKINNNDDNEKI
  
Inhibitor
Name:
BDBM50073054
Synonyms:
1-[4-Ethyl-1-(3-methoxymethoxy-phenyl)-cyclohexyl]-4-phenyl-piperazine | CHEMBL60737
Type:
Small organic molecule
Emp. Form.:
C26H36N2O2
Mol. Mass.:
408.5762
SMILES:
CC[C@H]1CC[C@](CC1)(N1CCN(CC1)c1ccccc1)c1cccc(OCOC)c1 |wU:5.8,2.1,(9.31,-1.88,;7.97,-2.65,;7.97,-4.19,;9.31,-4.96,;9.31,-6.51,;7.97,-7.28,;6.65,-6.51,;6.65,-4.96,;9.31,-8.05,;10.62,-7.28,;11.96,-8.05,;11.96,-9.59,;10.62,-10.34,;9.29,-9.59,;13.29,-10.37,;14.61,-9.59,;15.95,-10.37,;15.95,-11.91,;14.6,-12.68,;13.27,-11.91,;6.64,-8.05,;6.64,-9.61,;5.29,-10.38,;3.96,-9.61,;3.96,-8.07,;2.63,-7.3,;1.29,-8.07,;-.04,-7.3,;-1.38,-8.07,;5.29,-7.28,)|
Structure:
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