Reaction Details Report a problem with these data
Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50073326
Substrate
n/a
Meas. Tech.
ChEBML_157702
Ki
21000±n/a nM
Citation
 Han, W; Pelletier, JC; Hodge, CN Tricyclic ureas: a new class of HIV-1 protease inhibitors. Bioorg Med Chem Lett 8:3615-20 (1999) [PubMed]  Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50073326
Synonyms:
(2R,3R,4R)-4-Benzyl-2,3-dihydroxy-5,7-diaza-tricyclo[6.2.2.0*1,7*]dodecan-6-one | CHEMBL119973
Type:
Small organic molecule
Emp. Form.:
C17H22N2O3
Mol. Mass.:
302.3682
SMILES:
O[C@@H]1[C@@H](Cc2ccccc2)NC(=O)N2[C@H]3CC[C@@]2(CC3)[C@H]1O
Structure:
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