Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 1D
Ligand
BDBM50076428
Substrate
n/a
Meas. Tech.
ChEMBL_3532 (CHEMBL619199)
Ki
1±n/a nM
Citation
 Lang, L; Jagoda, E; Schmall, B; Vuong, BK; Adams, HR; Nelson, DL; Carson, RE; Eckelman, WC Development of fluorine-18-labeled 5-HT1A antagonists. J Med Chem 42:1576-86 (1999) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 1D
Synonyms:
5-hydroxytryptamine receptor 1D (5HT1D) | 5HT1D_MOUSE | Gpcr14 | Htr1d | Serotonin 1d (5-HT1d) receptor
Type:
Enzyme
Mol. Mass.:
41605.88
Organism:
Mus musculus (Mouse)
Description:
Q61224
Residue:
374
Sequence:
MSPPNQSLEGLPQEASNRSLNVTGAWDPEVLQALRISLVVVLSVITLATVLSNAFVLTTILLTKKLHTPANYLIGSLATTDLLVSILVMPISIAYTTTRTWNFGQILCDIWVSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAAVWIISICISIPPLFWRQATAHEEMSDCLVNTSQISYTIYSTCGAFYIPSILLIILYGRIYVAARSRILNPPSLYGKRFTTAQLITGSAGSSLCSLNPSLHESHTHTVGSPLFFNQVKIKLADSILERKRISAARERKATKTLGIILGAFIICWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPVIYTVFNEDFRQAFQKVVHFRKIS
  
Inhibitor
Name:
BDBM50076428
Synonyms:
4-Fluoro-cyclohexanecarboxylic acid {2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-pyridin-2-yl-amide | CHEMBL38413
Type:
Small organic molecule
Emp. Form.:
C25H33FN4O2
Mol. Mass.:
440.5535
SMILES:
COc1ccccc1N1CCN(CCN(C(=O)C2CCC(F)CC2)c2ccccn2)CC1 |(2.32,-7.79,;3.65,-8.56,;3.63,-10.1,;2.31,-10.86,;2.31,-12.41,;3.63,-13.18,;4.99,-12.41,;4.99,-10.87,;6.3,-10.12,;7.65,-10.89,;8.99,-10.12,;8.96,-8.58,;10.31,-7.82,;11.65,-8.58,;12.96,-7.82,;14.31,-8.58,;14.31,-10.13,;15.63,-7.82,;16.96,-8.58,;18.94,-8.27,;19.49,-9.96,;21.03,-9.96,;18.27,-9.22,;16.18,-9.51,;12.96,-6.27,;11.65,-5.51,;11.65,-3.96,;12.96,-3.19,;14.31,-3.96,;14.31,-5.51,;7.65,-7.81,;6.32,-8.58,)|
Structure:
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