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Target
Somatostatin receptor type 3
Ligand
BDBM50077285
Substrate
n/a
Meas. Tech.
ChEMBL_200829 (CHEMBL807042)
Ki
18±n/a nM
Citation
 Hocart, SJ; Jain, R; Murphy, WA; Taylor, JE; Coy, DH Highly potent cyclic disulfide antagonists of somatostatin. J Med Chem 42:1863-71 (1999) [PubMed]  Article 
Target
Name:
Somatostatin receptor type 3
Synonyms:
SOMATOSTATIN SST3 | SS-3-R | SS3-R | SS3R | SSR-28 | SSR3_HUMAN | SSTR3 | Somatostatin receptor type 3 (SSTR3)
Type:
Protein
Mol. Mass.:
45855.97
Organism:
Homo sapiens (Human)
Description:
P32745
Residue:
418
Sequence:
MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLLGNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVVFSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRVWAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVALPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEESREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL
  
Inhibitor
Name:
BDBM50077285
Synonyms:
10-(4-Amino-butyl)-19-[2-amino-3-(4-iodo-phenyl)-propionylamino]-13-(1H-indol-3-ylmethyl)-7-isopropyl-6,9,12,15,18-pentaoxo-16-pyridin-3-ylmethyl-1,2-dithia-5,8,11,14,17-pentaaza-cycloicosane-4-carboxylic acid [1-carbamoyl-2-(4-iodo-phenyl)-ethyl]-amide | CHEMBL264028
Type:
Small organic molecule
Emp. Form.:
C54H66I2N12O8S2
Mol. Mass.:
1329.116
SMILES:
CC(C)[C@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2cccnc2)NC(=O)[C@H](CSSC[C@@H](NC1=O)C(=O)N[C@@H](Cc1ccc(I)cc1)C(N)=O)NC(=O)[C@@H](N)Cc1ccc(I)cc1
Structure:
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