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TargetBeta-1 adrenergic receptor
LigandBDBM50078788
Substrate/Competitorn/a
Meas. Tech.ChEBML_37387
IC50 4000±n/a nM
Citation Mathvink, RJBarritta, AMCandelore, MRCascieri, MADeng, LTota, LStrader, CDWyvratt, MJFisher, MHWeber, AE Potent, elective human beta3 adrenergic receptor agonists containing a substituted indoline-5-sulfonamide pharmacophore. Bioorg Med Chem Lett9:1869-74 (1999) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Beta-1 adrenergic receptor
Name:Adrenergic receptor
Synonyms:B1AR | Beta-1 adrenoceptor | Beta-1 adrenoreceptor | adrenergic Beta1
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:51338.40
Organism:Homo sapiens (Human)
Description:n/a
Residue:477
Sequence:
MGAGVLVLGASEPGNLSSAAPLPDGAATAARLLVPASPPASLLPPASESPEPLSQQWTAG
MGLLMALIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVV
WGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARGLVC
TVWAISALVSFLPILMHWWRAESDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIM
AFVYLRVFREAQKQVKKIDSCERRFLGGPARPPSPSPSPVPAPAPPPGPPRPAAAAATAP
LANGRAGKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRELVPDRLFV
FFNWLGYANSAFNPIIYCRSPDFRKAFQRLLCCARRAARRRHATHGDRPRASGCLARPGP
PPSPGAASDDDDDDVVGATPPARLLEPWAGCNGGAAADSDSSLDEPCRPGFASESKV
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50078788
NameBDBM50078788
Synonyms:1-[3-(3-cyclopentylpropyl)phenyl]-N-phenyl-2,3-dihydro-1H-indole-5-sulfonamide | CHEMBL54750
TypeSmall organic molecule
Emp. Form.C28H32N2O2S
Mol. Mass.460.631
SMILESO=S(=O)(Nc1ccccc1)c1ccc2N(CCc2c1)c1cccc(CCCC2CCCC2)c1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a