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Target
5-hydroxytryptamine receptor 4
Ligand
BDBM50079939
Substrate
n/a
Meas. Tech.
ChEMBL_3316 (CHEMBL619016)
Ki
>1000±n/a nM
Citation
 Birch, AM; Bradley, PA; Gill, JC; Kerrigan, F; Needham, PL N-Substituted (2,3-dihydro-1,4-benzodioxin-2-yl)methylamine derivatives as D(2) antagonists/5-HT(1A) partial agonists with potential as atypical antipsychotic agents. J Med Chem 42:3342-55 (1999) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 4
Synonyms:
5-hydroxytryptamine receptor 4 protein | Serotonin 4 (5-HT4) receptor
Type:
PROTEIN
Mol. Mass.:
45024.02
Organism:
Sus scrofa
Description:
ChEMBL_1297282
Residue:
402
Sequence:
MDKLDANGSSKEGFGSVEKVVLLTFVSAVILMAVLGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDVWIYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRVAVLLAGCWAIPVLISFLPIMQGWNNIGITDLERTSKPRLGQDLHVIEKRKFHQNSNSTYCIFMVNKPYAITCSVVAFYIPFLLMVLAYWRIYVTAKEHAHQIQMLQRAGAPAEGRPPSADQHSTHRMRTETKAAKTLCVIMGCFCLCWAPFFVTNVVDPFADYSVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPCVAGQTVPCSTTTVNGSTHVLRDAVECGGQWESQCHPPATSPLVAAQPSDT
  
Inhibitor
Name:
BDBM50079939
Synonyms:
(7-Chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-[1-(2-methoxy-phenyl)-piperidin-4-ylmethyl]-amine | CHEMBL418854
Type:
Small organic molecule
Emp. Form.:
C22H27ClN2O3
Mol. Mass.:
402.914
SMILES:
COc1ccccc1N1CCC(CNCC2COc3ccc(Cl)cc3O2)CC1
Structure:
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