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Target
Serine protease 1
Ligand
BDBM50069294
Substrate
n/a
Meas. Tech.
ChEBML_212525
Ki
33000±n/a nM
Citation
 Lee, K; Jung, WH; Hwang, SY; Lee, SH Fluorobenzamidrazone thrombin inhibitors: influence of fluorine on enhancing oral absorption. Bioorg Med Chem Lett 9:2483-6 (1999) [PubMed]  Article 
Target
Name:
Serine protease 1
Synonyms:
Beta-Trypsin | Cationic trypsin | PRSS1 | TRP1 | TRY1 | TRY1_BOVIN | TRYP1 | Trypsin | Trypsin I
Type:
Enzyme
Mol. Mass.:
25790.52
Organism:
Bos taurus (bovine)
Description:
P00760
Residue:
246
Sequence:
MKTFIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN
  
Inhibitor
Name:
BDBM50069294
Synonyms:
(S)-3-[4-(carbohydrazonamidol)-phenyl]-N-cyclopentyl-N-methyl-2-(naphthalene-2-sulfonylamino)-propionamide | (S)-5-(4-Methylamino-phenyl)-2-(5,6,7,8-tetrahydro-naphthalene-2-sulfonylamino)-pent-4-ynoic acid cyclopentylamide | 1N-cyclopentyl-1N-methyl-3-(4-Carbohydrazonamidephenyl)-2-(2-naphthylsulfonamido)-(2S)-propanamide | 1N-cyclopentyl-3-[4-amino(aminoimino)methylphenyl]-2-(2-naphthylsulfinamido)propanamide | Benzamidrazone analogue | CHEMBL7962 | N-methyl-N-cyclopentyl-3-(4-hydrazonoformamidephenyl)-2-[(2-naphthylsulfonyl)amino]propanamide
Type:
Small organic molecule
Emp. Form.:
C26H31N5O3S
Mol. Mass.:
493.621
SMILES:
CN(C1CCCC1)C(=O)[C@H](Cc1ccc(cc1)C(N)=NN)NS(=O)(=O)c1ccc2ccccc2c1 |w:19.21|
Structure:
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