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Target
Transcriptional activator protein LasR
Ligand
BDBM50526982
Substrate
n/a
Meas. Tech.
ChEMBL_1901852 (CHEMBL4404074)
IC50
9700±n/a nM
Citation
 Chbib, C Impact of the structure-activity relationship of AHL analogues on quorum sensing in Gram-negative bacteria. Bioorg Med Chem 28:0 (2020) [PubMed]  Article 
Target
Name:
Transcriptional activator protein LasR
Synonyms:
LASR_PSEAE | lasR
Type:
PROTEIN
Mol. Mass.:
26618.24
Organism:
Pseudomonas aeruginosa
Description:
ChEMBL_1475312
Residue:
239
Sequence:
MALVDGFLELERSSGKLEWSAILQKMASDLGFSKILFGLLPKDSQDYENAFIVGNYPAAWREHYDRAGYARVDPTVSHCTQSVLPIFWEPSIYQTRKQHEFFEEASAAGLVYGLTMPLHGARGELGALSLSVEAENRAEANRFMESVLPTLWMLKDYALQSGAGLAFEHPVSKPVVLTSREKEVLQWCAIGKTSWEISVICNCSEANVNFHMGNIRRKFGVTSRRVAAIMAVNLGLITL
  
Inhibitor
Name:
BDBM50526982
Synonyms:
CHEMBL4549418
Type:
Small organic molecule
Emp. Form.:
C11H13NO2
Mol. Mass.:
191.2264
SMILES:
CCC(=O)CC(=O)Nc1ccccc1
Structure:
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