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Target
Transcriptional activator protein LasR
Ligand
BDBM50351511
Substrate
n/a
Meas. Tech.
ChEMBL_1901852 (CHEMBL4404074)
IC50
5500±n/a nM
Citation
 Chbib, C Impact of the structure-activity relationship of AHL analogues on quorum sensing in Gram-negative bacteria. Bioorg Med Chem 28:0 (2020) [PubMed]  Article 
Target
Name:
Transcriptional activator protein LasR
Synonyms:
LASR_PSEAE | lasR
Type:
PROTEIN
Mol. Mass.:
26618.24
Organism:
Pseudomonas aeruginosa
Description:
ChEMBL_1475312
Residue:
239
Sequence:
MALVDGFLELERSSGKLEWSAILQKMASDLGFSKILFGLLPKDSQDYENAFIVGNYPAAWREHYDRAGYARVDPTVSHCTQSVLPIFWEPSIYQTRKQHEFFEEASAAGLVYGLTMPLHGARGELGALSLSVEAENRAEANRFMESVLPTLWMLKDYALQSGAGLAFEHPVSKPVVLTSREKEVLQWCAIGKTSWEISVICNCSEANVNFHMGNIRRKFGVTSRRVAAIMAVNLGLITL
  
Inhibitor
Name:
BDBM50351511
Synonyms:
CHEMBL463321
Type:
Small organic molecule
Emp. Form.:
C12H19NO4
Mol. Mass.:
241.2836
SMILES:
CCCCCC(=O)CC(=O)N[C@H]1CCOC1=O |r|
Structure:
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