Reaction Details Report a problem with these data
Target
Anionic trypsin
Ligand
BDBM50082182
Substrate
n/a
Meas. Tech.
ChEBML_212167
Ki
440.0±n/a nM
Citation
 Stürzebecher, J; Vieweg, H; Steinmetzer, T; Schweinitz, A; Stubbs, MT; Renatus, M; Wikström, P 3-Amidinophenylalanine-based inhibitors of urokinase. Bioorg Med Chem Lett 9:3147-52 (1999) [PubMed]  Article 
Target
Name:
Anionic trypsin
Synonyms:
Anionic trypsin | TRY2_BOVIN | Trypsin II
Type:
PROTEIN
Mol. Mass.:
26281.39
Organism:
Bos taurus
Description:
ChEMBL_212177
Residue:
247
Sequence:
MHPLLILAFVGAAVAFPSDDDDKIVGGYTCAENSVPYQVSLNAGYHFCGGSLINDQWVVSAAHCYQYHIQVRLGEYNIDVLEGGEQFIDASKIIRHPKYSSWTLDNDILLIKLSTPAVINARVSTLLLPSACASAGTECLISGWGNTLSSGVNYPDLLQCLVAPLLSHADCEASYPGQITNNMICAGFLEGGKDSCQGDSGGPVACNGQLQGIVSWGYGCAQKGKPGVYTKVCNYVDWIQETIAANS
  
Inhibitor
Name:
BDBM50082182
Synonyms:
3-[2-(Naphthalene-2-sulfonylamino)-3-oxo-3-pyrrolidin-1-yl-propyl]-benzamidine | CHEMBL106869
Type:
Small organic molecule
Emp. Form.:
C24H26N4O3S
Mol. Mass.:
450.553
SMILES:
NC(=N)c1cccc(CC(NS(=O)(=O)c2ccc3ccccc3c2)C(=O)N2CCCC2)c1
Structure:
Search PDB for entries with ligand similarity: