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Target
Neutral alpha-glucosidase C
Ligand
BDBM50082234
Substrate
n/a
Meas. Tech.
ChEBML_34249
IC50
22±n/a nM
Citation
 Martin, OR; Compain, P; Kizu, H; Asano, N Revised structure of a homonojirimycin isomer from Aglaonema treubii: first example of a naturally occurring alpha-homoallonojirimycin. Bioorg Med Chem Lett 9:3171-4 (1999) [PubMed]  Article 
Target
Name:
Neutral alpha-glucosidase C
Synonyms:
GANC | GANC_HUMAN
Type:
PROTEIN
Mol. Mass.:
104326.35
Organism:
Homo sapiens (Human)
Description:
ChEMBL_34249
Residue:
914
Sequence:
MEAAVKEEISLEDEAVDKNIFRDCNKIAFYRRQKQWLSKKSTYQALLDSVTTDEDSTRFQIINEASKVPLLAEIYGIEGNIFRLKINEETPLKPRFEVPDVLTSKPSTVRLISCSGDTGSLILADGKGDLKCHITANPFKVDLVSEEEVVISINSLGQLYFEHLQILHKQRAAKENEEETSVDTSQENQEDLGLWEEKFGKFVDIKANGPSSIGLDFSLHGFEHLYGIPQHAESHQLKNTGDGDAYRLYNLDVYGYQIYDKMGIYGSVPYLLAHKLGRTIGIFWLNASETLVEINTEPAVEYTLTQMGPVAAKQKVRSRTHVHWMSESGIIDVFLLTGPTPSDVFKQYSHLTGTQAMPPLFSLGYHQCRWNYEDEQDVKAVDAGFDEHDIPYDAMWLDIEHTEGKRYFTWDKNRFPNPKRMQELLRSKKRKLVVISDPHIKIDPDYSVYVKAKDQGFFVKNQEGEDFEGVCWPGLSSYLDFTNPKVREWYSSLFAFPVYQGSTDILFLWNDMNEPSVFRGPEQTMQKNAIHHGNWEHRELHNIYGFYHQMATAEGLIKRSKGKERPFVLTRSFFAGSQKYGAVWTGDNTAEWSNLKISIPMLLTLSITGISFCGADIGGFIGNPETELLVRWYQAGAYQPFFRGHATMNTKRREPWLFGEEHTRLIREAIRERYGLLPYWYSLFYHAHVASQPVMRPLWVEFPDELKTFDMEDEYMLGSALLVHPVTEPKATTVDVFLPGSNEVWYDYKTFAHWEGGCTVKIPVALDTIPVFQRGGSVIPIKTTVGKSTGWMTESSYGLRVALSTKGSSVGELYLDDGHSFQYLHQKQFLHRKFSFCSSVLINSFADQRGHYPSKCVVEKILVLGFRKEPSSVTTHSSDGKDQPVAFTYCAKTSILSLEKLSLNIATDWEVRII
  
Inhibitor
Name:
BDBM50082234
Synonyms:
(3R,4R,5S)-2,6-Bis-hydroxymethyl-piperidine-3,4,5-triol | CHEMBL320116
Type:
Small organic molecule
Emp. Form.:
C7H15NO5
Mol. Mass.:
193.1977
SMILES:
OCC1NC(CO)[C@H](O)[C@@H](O)[C@@H]1O
Structure:
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