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Target
Peroxisome proliferator-activated receptor delta
Ligand
BDBM50075315
Substrate
n/a
Meas. Tech.
ChEMBL_139147 (CHEMBL747680)
EC50
7200±n/a nM
Citation
 Willson, TM; Brown, PJ; Sternbach, DD; Henke, BR The PPARs: from orphan receptors to drug discovery. J Med Chem 43:527-50 (2000) [PubMed]  Article 
Target
Name:
Peroxisome proliferator-activated receptor delta
Synonyms:
NUC1 | Nr1c2 | Nuclear hormone receptor 1 | Nuclear receptor subfamily 1 group C member 2 | PPAR-beta | PPAR-delta | PPARD_MOUSE | Pparb | Ppard
Type:
PROTEIN
Mol. Mass.:
49719.14
Organism:
Mus musculus
Description:
ChEMBL_1288931
Residue:
440
Sequence:
MEQPQEETPEAREEEKEEVAMGDGAPELNGGPEHTLPSSSCADLSQNSSPSSLLDQLQMGCDGASGGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCDRICKIQKKNRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTASEGCQHNPQLADLKAFSKHIYNAYLKNFNMTKKKARSILTGKSSHNAPFVIHDIETLWQAEKGLVWKQLVNGLPPYNEISVHVFYRCQSTTVETVRELTEFAKNIPNFSSLFLNDQVTLLKYGVHEAIFAMLASIVNKDGLLVANGSGFVTHEFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGDRPGLMNVPQVEAIQDTILRALEFHLQVNHPDSQYLFPKLLQKMADLRQLVTEHAQMMQWLKKTESETLLHPLLQEIYKDMY
  
Inhibitor
Name:
BDBM50075315
Synonyms:
5-(2,4-Dioxo-thiazolidin-5-ylmethyl)-2-methoxy-N-(4-trifluoromethyl-benzyl)-benzamide | 5-(2,4-Dioxo-thiazolidin-5-ylmethyl)-2-methoxy-N-(4-trifluoromethyl-benzyl)-benzamide(KRP297) | CHEMBL24458 | KRP-297
Type:
Small organic molecule
Emp. Form.:
C20H17F3N2O4S
Mol. Mass.:
438.42
SMILES:
COc1ccc(Cc2sc(=O)[nH]c2O)cc1C(=O)NCc1ccc(cc1)C(F)(F)F
Structure:
Search PDB for entries with ligand similarity: