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Target
Adenosine receptor A3
Ligand
BDBM81925
Substrate
n/a
Meas. Tech.
ChEMBL_31867 (CHEMBL644388)
Ki
1300±n/a nM
Citation
 Colotta, V; Catarzi, D; Varano, F; Cecchi, L; Filacchioni, G; Martini, C; Trincavelli, L; Lucacchini, A 1,2,4-Triazolo[4,3-a]quinoxalin-1-one: a versatile tool for the synthesis of potent and selective adenosine receptor antagonists. J Med Chem 43:1158-64 (2000) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM81925
Synonyms:
8-Cyclopentyl-1,3-dimethyl-3,7-dihydro-purine-2,6-dione | 8-Cyclopentyltheophylline (CPT) | CAS_1917 | CHEMBL106265 | CPT | NSC_1917
Type:
Small organic molecule
Emp. Form.:
C12H16N4O2
Mol. Mass.:
248.281
SMILES:
Cn1c2nc([nH]c2c(=O)n(C)c1=O)C1CCCC1
Structure:
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