Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50088459
Substrate
n/a
Meas. Tech.
ChEMBL_31844 (CHEMBL641521)
Ki
1260000±n/a nM
Citation
 van Muijlwijk-Koezen, JE; Timmerman, H; van der Goot, H; Menge, WM; Frijtag Von Drabbe Künzel, J; de Groote, M; IJzerman, AP Isoquinoline and quinazoline urea analogues as antagonists for the human adenosine A(3) receptor. J Med Chem 43:2227-38 (2000) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50088459
Synonyms:
1-[2-(4,6-Dimethyl-pyrimidin-2-yl)-quinazolin-4-yl]-3-phenyl-urea | CHEMBL72030
Type:
Small organic molecule
Emp. Form.:
C21H18N6O
Mol. Mass.:
370.4072
SMILES:
Cc1cc(C)nc(n1)-c1nc(NC(=O)Nc2ccccc2)c2ccccc2n1
Structure:
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