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Target
Mu-type opioid receptor
Ligand
BDBM50088724
Substrate
n/a
Meas. Tech.
ChEBML_148989
Ki
94±n/a nM
Citation
 Boyd, RE; Carson, JR; Codd, EE; Gauthier, AD; Neilson, LA; Zhang, SP Synthesis and binding affinities of 4-diarylaminotropanes, a new class of delta opioid agonists. Bioorg Med Chem Lett 10:1109-11 (2000) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
MOR-1 | MUOR1 | Mu-type opioid receptor (MOR) | OPIATE Mu | OPRM_RAT | Opiate non-selective | Opioid receptor B | Oprm1 | Ror-b
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44503.11
Organism:
Rattus norvegicus (rat)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the mu opioid receptor.
Residue:
398
Sequence:
MDSSTGPGNTSDCSDPLAQASCSPAPGSWLNLSHVDGNQSDPCGLNRTGLGGNDSLCPQTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSTRVRQNTREHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50088724
Synonyms:
CHEMBL275011 | N,N-Diethyl-4-{[(1R,3R,5S)-8-(3-methyl-but-2-enyl)-8-aza-bicyclo[3.2.1]oct-3-yl]-phenyl-amino}-benzamide
Type:
Small organic molecule
Emp. Form.:
C29H39N3O
Mol. Mass.:
445.6395
SMILES:
[#6]-[#6]-[#7](-[#6]-[#6])-[#6](=O)-c1ccc(cc1)-[#7](-[#6@@H]-1-[#6]-[#6@@H]-2-[#6]-[#6]-[#6@H](-[#6]-1)-[#7]-2-[#6]\[#6]=[#6](\[#6])-[#6])-c1ccccc1 |THB:22:21:14.20.15:17.18|
Structure:
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