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Target
Mu-type opioid receptor
Ligand
BDBM50088746
Substrate
n/a
Meas. Tech.
ChEBML_148989
Ki
1420±n/a nM
Citation
 Boyd, RE; Carson, JR; Codd, EE; Gauthier, AD; Neilson, LA; Zhang, SP Synthesis and binding affinities of 4-diarylaminotropanes, a new class of delta opioid agonists. Bioorg Med Chem Lett 10:1109-11 (2000) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
MOR-1 | MUOR1 | Mu-type opioid receptor (MOR) | OPIATE Mu | OPRM_RAT | Opiate non-selective | Opioid receptor B | Oprm1 | Ror-b
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44503.11
Organism:
Rattus norvegicus (rat)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the mu opioid receptor.
Residue:
398
Sequence:
MDSSTGPGNTSDCSDPLAQASCSPAPGSWLNLSHVDGNQSDPCGLNRTGLGGNDSLCPQTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSTRVRQNTREHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50088746
Synonyms:
4-{[(1S,3R,5R)-8-(2,2-Diphenyl-ethyl)-8-aza-bicyclo[3.2.1]oct-3-yl]-phenyl-amino}-N,N-diethyl-benzamide | CHEMBL406783
Type:
Small organic molecule
Emp. Form.:
C38H43N3O
Mol. Mass.:
557.7675
SMILES:
CCN(CC)C(=O)c1ccc(cc1)N([C@@H]1C[C@@H]2CC[C@H](C1)N2CC(c1ccccc1)c1ccccc1)c1ccccc1 |THB:22:21:14.15.20:17.18|
Structure:
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