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Target
Serine protease 1
Ligand
BDBM50088918
Substrate
n/a
Meas. Tech.
ChEBML_212535
Ki
90±n/a nM
Citation
 Arnaiz, DO; Zhao, Z; Liang, A; Trinh, L; Witlow, M; Koovakkat, SK; Shaw, KJ Design, synthesis, and in vitro biological activity of indole-based factor Xa inhibitors. Bioorg Med Chem Lett 10:957-61 (2000) [PubMed]  Article 
Target
Name:
Serine protease 1
Synonyms:
Alpha-trypsin chain 1 | Alpha-trypsin chain 2 | Beta-trypsin | Cationic trypsinogen | PRSS1 | Serine protease 1 | TRP1 | TRY1 | TRY1_HUMAN | TRYP1 | Thrombin & trypsin | Trypsin | Trypsin I | Trypsin-1
Type:
Enzyme
Mol. Mass.:
26557.80
Organism:
Homo sapiens (Human)
Description:
P07477
Residue:
247
Sequence:
MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAANS
  
Inhibitor
Name:
BDBM50088918
Synonyms:
2-[9-(7-Carbamimidoyl-naphthalen-2-ylmethyl)-9H-carbazol-2-yloxy]-N,N-dimethyl-acetamide | CHEMBL174995
Type:
Small organic molecule
Emp. Form.:
C28H26N4O2
Mol. Mass.:
450.5316
SMILES:
CN(C)C(=O)COc1ccc2c(c1)n(Cc1ccc3ccc(cc3c1)C(N)=N)c1ccccc21
Structure:
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