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Target
Gastrin-releasing peptide receptor
Ligand
BDBM50005601
Substrate
n/a
Meas. Tech.
ChEMBL_39236 (CHEMBL655732)
Ki
>0.000±n/a nM
Comments
>0.000010 20220122
Citation
 Cristau, M; Devin, C; Oiry, C; Chaloin, O; Amblard, M; Bernad, N; Heitz, A; Fehrentz, JA; Martinez, J Synthesis and biological evaluation of bombesin constrained analogues. J Med Chem 43:2356-61 (2000) [PubMed]  Article 
Target
Name:
Gastrin-releasing peptide receptor
Synonyms:
GRPR_RAT | Gastrin-Releasing peptide | Gastrin-releasing peptide receptor | Grpr
Type:
Enzyme Catalytic Domain
Mol. Mass.:
43227.55
Organism:
RAT
Description:
Gastrin-Releasing peptide 0 RAT::P52500
Residue:
384
Sequence:
MDPNNCSHLNLEVDPFLSCNNTFNQTLSPPKMDNWFHPGIIYVIPAVYGLIIVIGLIGNITLIKIFCTVKSMRNVPNLFISSLALGDLLLLVTCAPVDASKYLADRWLFGRIGCKLIPFIQLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLKAALIWIVSMLLAIPEAVFSDLHPFHVKDTNQTFISCAPYPHSNELHPKIHSMASFLVFYIIPLSIISVYYYFIARNLIQSAYNLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSYHYSEVDTSMLHFITSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPSLLNRSHSTGRSTTCMTSFKSTNPSATFSLINGNICHEGYV
  
Inhibitor
Name:
BDBM50005601
Synonyms:
CHEMBL2369819
Type:
Small organic molecule
Emp. Form.:
C58H76N14O10
Mol. Mass.:
1129.3118
SMILES:
CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H]1C[C@@H](CN1C(=O)c1ccccc1)NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](N)Cc1ccccc1)C(N)=O
Structure:
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