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TargetAtrial natriuretic peptide receptor
LigandBDBM50091748
Substrate/Competitorn/a
Meas. Tech.ChEBML_34991
Ki 680±n/a nM
Citation Veale, CAAlford, VCAharony, DBanville, DLBialecki, RABrown, FJDamewood, JRDantzman, CLEdwards, PDJacobs, RTMauger, RCMurphy, MMPalmer, WPine, KKRumsey, WLGarcia-Davenport, LEShaw, ASteelman, GBSurian, JMVacek, EP The discovery of non-basic atrial natriuretic peptide clearance receptor antagonists. Part 1. Bioorg Med Chem Lett10:1949-52 (2001) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Atrial natriuretic peptide receptor
Name:Atrial natriuretic peptide receptor
Synonyms:ANP-C | ANPRC | Atrial natriuretic peptide C-type receptor | Atrial natriuretic peptide clearance receptor | Atrial natriuretic peptide receptor C | NPR-C
Type:PROTEIN
Mol. Mass.:59805.12
Organism:Homo sapiens
Description:ChEMBL_34991
Residue:541
Sequence:
MPSLLVLTFSPCVLLGWALLAGGTGGGGVGGGGGGAGIGGGRQEREALPPQKIEVLVLLP
QDDSYLFSLTRVRPAIEYALRSVEGNGTGRRLLPPGTRFQVAYEDSDCGNRALFSLVDRV
AAARGAKPDLILGPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDSEYSHLTRVAPA
YAKMGEMMLALFRHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGLHTSIYSFDETK
DLDLEDIVRNIQASERVVIMCASSDTIRSIMLVAHRHGMTSGDYAFFNIELFNSSSYGDG
SWKRGDKHDFEAKQAYSSLQTVTLLRTVKPEFEKFSMEVKSSVEKQGLNMEDYVNMFVEG
FHDAILLYVLALHEVLRAGYSKKDGGKIIQQTWNRTFEGIAGQVSIDANGDRYGDFSVIA
MTDVEAGTQEVIGDYFGKEGRFEMRPNVKYPWGPLKLRIDENRIVEHTNSSPCKSSGGLE
ESAVTGIVVGALLGAGLLMAFYFFRKKYRITIERRTQQEESNLGKHRELREDSIRSHFSV
A
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  Blast E-value cutoff:
BDBM50091748
NameBDBM50091748
Synonyms:(S)-N-[(S)-4-Guanidino-1-((S)-2-methyl-butylcarbamoyl)-butyl]-3-{(S)-2-[(S)-5-guanidino-2-(2-{4-[(naphthalene-2-carbonyl)-amino]-phenyl}-acetylamino)-pentanoylamino]-propionylamino}-succinamic acid | CHEMBL294262
TypeSmall organic molecule
Emp. Form.C43H60N12O8
Mol. Mass.873.0121
SMILESCC[C@H](C)CNC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)Cc1ccc(NC(=O)c2ccc3ccccc3c2)cc1
Structure
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n/a