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Target
D(2) dopamine receptor
Ligand
BDBM50095042
Substrate
n/a
Meas. Tech.
ChEBML_60046
Ki
21±n/a nM
Citation
 Stevenson, GI; Smith, AL; Lewis, S; Michie, SG; Neduvelil, JG; Patel, S; Marwood, R; Patel, S; Castro, JL 2-Aryl tryptamines: selective high-affinity antagonists for the h5-HT2A receptor. Bioorg Med Chem Lett 10:2697-9 (2000) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50095042
Synonyms:
3-[2-((R)-2-Methyl-piperidin-1-yl)-ethyl]-2-phenyl-1H-indole | CHEMBL90263
Type:
Small organic molecule
Emp. Form.:
C22H26N2
Mol. Mass.:
318.4552
SMILES:
C[C@@H]1CCCCN1CCc1c([nH]c2ccccc12)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: