Reaction Details Report a problem with these data
Target
Histamine H3 receptor
Ligand
BDBM50092833
Substrate
n/a
Meas. Tech.
ChEBML_86751
Ki
4.9±n/a nM
Citation
 Stark, H; Sippl, W; Ligneau, X; Arrang, JM; Ganellin, CR; Schwartz, JC; Schunack, W Different antagonist binding properties of human and rat histamine H3 receptors. Bioorg Med Chem Lett 11:951-4 (2001) [PubMed]  Article 
Target
Name:
Histamine H3 receptor
Synonyms:
HH3R | HRH3_RAT | Hrh3
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
48607.98
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
445
Sequence:
MERAPPDGLMNASGTLAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVEAGEAALGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGRCIPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK
  
Inhibitor
Name:
BDBM50092833
Synonyms:
4-(3-Phenoxy-propyl)-1H-imidazole with (0.95M)oxalic acid | CHEMBL112951 | CHEMBL128923
Type:
Small organic molecule
Emp. Form.:
C12H14N2O
Mol. Mass.:
202.2524
SMILES:
C(COc1ccccc1)Cc1cnc[nH]1
Structure:
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