Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 5
Ligand
BDBM50103711
Substrate
n/a
Meas. Tech.
ChEBML_140799
IC50
178±n/a nM
Citation
 Kordik, CP; Luo, C; Zanoni, BC; Dax, SL; McNally, JJ; Lovenberg, TW; Wilson, SJ; Reitz, AB Aminopyrazoles with high affinity for the human neuropeptide Y5 receptor. Bioorg Med Chem Lett 11:2283-6 (2001) [PubMed]  Article 
Target
Name:
Neuropeptide Y receptor type 5
Synonyms:
NPY-Y5 | NPY-Y5 receptor | NPY5-R | NPY5R | NPY5R_HUMAN | NPYR5 | NPYY5 | Neuropeptide Y receptor type 5 | Neuropeptide Y receptor type 5 ( NPY Y5) | Y5 receptor
Type:
Enzyme
Mol. Mass.:
50746.64
Organism:
Homo sapiens (Human)
Description:
Q15761
Residue:
445
Sequence:
MDLELDEYYNKTLATENNTAATRNSDFPVWDDYKSSVDDLQYFLIGLYTFVSLLGFMGNLLILMALMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKVMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSLVELQETFGSALLSSRYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISCGLSNKENRLEENEMINLTLHPSKKSGPQVKLSGSHKWSYSFIKKHRRRYSKKTACVLPAPERPSQENHSRILPENFGSVRSQLSSSSKFIPGVPTCFEIKPEENSDVHELRVKRSVTRIKKRSRSVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCLNPILYGFLNNGIKADLVSLIHCLHM
  
Inhibitor
Name:
BDBM50103711
Synonyms:
CHEMBL307901 | N-[4-(5-Amino-1-p-tolyl-1H-pyrazol-3-yl)-phenyl]-2-nitro-benzenesulfonamide
Type:
Small organic molecule
Emp. Form.:
C22H19N5O4S
Mol. Mass.:
449.482
SMILES:
Cc1ccc(cc1)-n1nc(cc1N)-c1ccc(NS(=O)(=O)c2ccccc2[N+]([O-])=O)cc1
Structure:
Search PDB for entries with ligand similarity: