Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50103756
Substrate
n/a
Meas. Tech.
ChEBML_31692
Ki
21600±n/a nM
Citation
 Ravi, G; Lee, K; Ji, X; Kim, HS; Soltysiak, KA; Marquez, VE; Jacobson, KA Synthesis and purine receptor affinity of 6-oxopurine nucleosides and nucleotides containing (N)-methanocarba-pseudoribose rings. Bioorg Med Chem Lett 11:2295-300 (2001) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50103756
Synonyms:
CHEMBL308634 | dimer[Phosphoric acid mono-[(1R,2R,3S,4R,5S)-2,3-dihydroxy-4-(6-hydroxy-purin-9-yl)-bicyclo[3.1.0]hex-1-ylmethyl] ester]
Type:
Small organic molecule
Emp. Form.:
C24H28N8O13P2
Mol. Mass.:
698.4724
SMILES:
O[C@@H]1[C@H](O)[C@]2(COP(O)(=O)OP(O)(=O)OC[C@@]34C[C@@H]3[C@H]([C@H](O)[C@@H]4O)n3cnc4c3nc[nH]c4=O)C[C@@H]2[C@H]1n1cnc2c1nc[nH]c2=O
Structure:
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