Reaction Details Report a problem with these data
Target
Chymotrypsinogen A
Ligand
BDBM50104174
Substrate
n/a
Meas. Tech.
ChEMBL_216786 (CHEMBL817062)
Ki
770±n/a nM
Citation
 Harvey, AJ; Abell, AD Alpha-ketoester-based photobiological switches: synthesis, peptide chain extension and assay against alpha-chymotrypsin. Bioorg Med Chem Lett 11:2441-4 (2001) [PubMed]  Article 
Target
Name:
Chymotrypsinogen A
Synonyms:
Alpha-chymotrypsin | CTRA_BOVIN | Chymotrypsin A | Chymotrypsin A chain A | Chymotrypsin A chain B | Chymotrypsin A chain C | Chymotrypsinogen A | alpha-Chymotrypsin (α-Chymotrypsin)
Type:
Serine protease
Mol. Mass.:
25670.88
Organism:
Bos taurus (bovine)
Description:
n/a
Residue:
245
Sequence:
CGVPAIQPVLSGLSRIVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGVTTSDVVVAGEFDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSASDDFAAGTTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCKKYWGTKIKDAMICAGASGVSSCMGDSGGPLVCKKNGAWTLVGIVSWGSSTCSTSTPGVYARVTALVNWVQQTLAAN
  
Inhibitor
Name:
BDBM50104174
Synonyms:
(S)-2-Oxo-4-phenyl-3-(4-phenylazo-benzyloxycarbonylamino)-butyric acid methyl ester | CHEMBL83560
Type:
Small organic molecule
Emp. Form.:
C25H23N3O5
Mol. Mass.:
445.4672
SMILES:
COC(=O)C(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccc(cc1)N=Nc1ccccc1 |w:26.28|
Structure:
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