| Reaction Details |
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 | Report a problem with these data |
| Target | Serine protease 1 |
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| Ligand | BDBM50097771 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_225790 |
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| Ki | 980±n/a nM |
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| Citation |  Liebeschuetz, JW; Jones, SD; Morgan, PJ; Murray, CW; Rimmer, AD; Roscoe, JM; Waszkowycz, B; Welsh, PM; Wylie, WA; Young, SC; Martin, H; Mahler, J; Brady, L; Wilkinson, K PRO_SELECT: combining structure-based drug design and array-based chemistry for rapid lead discovery. 2. The development of a series of highly potent and selective factor Xa inhibitors. J Med Chem45:1221-32 (2002) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine protease 1 |
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| Name: | Serine protease 1 |
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| Synonyms: | Beta-Trypsin | Cationic trypsin | Trypsin | Trypsin I |
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| Type: | Enzyme |
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| Mol. Mass.: | 25790.52 |
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| Organism: | Bos taurus (bovine) |
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| Description: | P00760 |
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| Residue: | 246 |
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| Sequence: | MKTFIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVS
AAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLN
SRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQIT
SNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIK
QTIASN
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| BDBM50097771 |
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| Name | BDBM50097771 |
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| Synonyms: | 3-[(Z)-AMINO(IMINO)METHYL]-N-[2-(4-BENZOYL-1-PIPERIDINYL)-2-OXO-1-PHENYLETHYL]BENZAMIDE | CHEMBL283765 | N-[(R)-2-(4-Benzoyl-piperidin-1-yl)-2-oxo-1-phenyl-ethyl]-3-carbamimidoyl-benzamide | N-[2-(4-Benzoyl-piperidin-1-yl)-2-oxo-1-phenyl-ethyl]-3-carbamimidoyl-benzamide |
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| Type | Small organic molecule |
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| Emp. Form. | C28H28N4O3 |
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| Mol. Mass. | 468.5469 |
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| SMILES | NC(=N)c1cccc(c1)C(=O)N[C@@H](C(=O)N1CCC(CC1)C(=O)c1ccccc1)c1ccccc1 |
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| Structure |  |
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| n/a |
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