Reaction Details Report a problem with these data
Target
Translocator protein
Ligand
BDBM50131400
Substrate
n/a
Meas. Tech.
ChEMBL_2045208 (CHEMBL4699907)
Ki
652±n/a nM
Citation
 Vo, SV; Banister, SD; Freelander, I; Werry, EL; Reekie, TA; Ittner, LM; Kassiou, M Reversing binding sensitivity to A147T translocator protein. RSC Med Chem 11:511-517 (2020) [PubMed]  Article 
Target
Name:
Translocator protein
Synonyms:
BZRP | MBR | Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor-related protein | Peripheral-type benzodiazepine receptor | TSPO | TSPO_HUMAN
Type:
Enzyme
Mol. Mass.:
18834.74
Organism:
Homo sapiens (Human)
Description:
P30536
Residue:
169
Sequence:
MAPPWVPAMGFTLAPSLGCFVGSRFVHGEGLRWYAGLQKPSWHPPHWVLGPVWGTLYSAMGYGSYLVWKELGGFTEKAVVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLLLVSGAAAATTVAWYQVSPLAARLLYPYLAWLAFTTTLNYCVWRDNHGWRGGRRLPE
  
Inhibitor
Name:
BDBM50131400
Synonyms:
CHEMBL3634876
Type:
Small organic molecule
Emp. Form.:
C23H28N2O2
Mol. Mass.:
364.4806
SMILES:
CCN(CC)C(=O)Cn1c(cc2c(C)cc(C)cc12)-c1ccc(OC)cc1
Structure:
Search PDB for entries with ligand similarity: