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Target
Amine oxidase [flavin-containing] B
Ligand
BDBM50116062
Substrate
n/a
Meas. Tech.
ChEBML_123920
IC50
121000±n/a nM
Citation
 Sciotti, RJ; Pliushchev, M; Wiedeman, PE; Balli, D; Flamm, R; Nilius, AM; Marsh, K; Stolarik, D; Jolly, R; Ulrich, R; Djuric, SW The synthesis and biological evaluation of a novel series of antimicrobials of the oxazolidinone class. Bioorg Med Chem Lett 12:2121-3 (2002) [PubMed]  Article 
Target
Name:
Amine oxidase [flavin-containing] B
Synonyms:
AOFB_RAT | Amine oxidase (flavin-containing) B | Amine oxidase [flavin-containing] B | Maob | Monoamine Oxidase Type B (MAO-B) | Monoamine oxidase | Monoamine oxidase B (MAO-B) | Monoamine oxidase B (rMAO-B) | Monoamine oxidase type B (MAOB) | Monoamine oxidase-B (MAO-B)
Type:
Enzyme
Mol. Mass.:
58469.65
Organism:
Rattus norvegicus (rat)
Description:
P19643
Residue:
520
Sequence:
MSNKCDVIVVGGGISGMAAAKLLHDCGLSVVVLEARDRVGGRTYTIRNKNVKYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHFVKGKSYAFRGPFPPVWNPITYLDYNNLWRTMDEMGQEIPSDAPWKAPLAEEWDYMTMKELLDKICWTNSTKQIATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFIGGSGQVSERIKDILGDRVKLERPVIHIDQTGENVVVKTLNHEIYEAKYVISAIPPVLGMKIHHSPPLPILRNQLITRVPLGSVIKCMVYYKEPFWRKKDFCGTMVIEGEEAPIAYTLDDTKPDGSCAAIMGFILAHKARKLVRLTKEERLRKLCELYAKVLNSQEALQPVHYEEKNWCEEQYSGGCYTAYFPPGILTQYGRVLRQPVGKIFFAGTETASHWSGYMEGAVEAGERAAREILHAIGKIPEDEIWQPEPESVDVPARPITNTFLERHLPSVPGLLKLLGLTTILSATALGFLAHKKGLFVRF
  
Inhibitor
Name:
BDBM50116062
Synonyms:
CHEMBL67796 | N-{(S)-3-[4-((Z)-2-Bromo-2-pyridin-3-yl-vinyl)-3-fluoro-phenyl]-2-oxo-oxazolidin-5-ylmethyl}-acetamide
Type:
Small organic molecule
Emp. Form.:
C19H17BrFN3O3
Mol. Mass.:
434.259
SMILES:
CC(=O)NC[C@H]1CN(C(=O)O1)c1ccc(\C=C(/Br)c2cccnc2)c(F)c1
Structure:
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