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Target
Kappa-type opioid receptor
Ligand
BDBM50116659
Substrate
n/a
Meas. Tech.
ChEBML_145839
Ki
5.7±n/a nM
Citation
 Mou, QY; Chen, J; Zhu, YC; Zhou, DH; Chi, ZQ; Long, YQ 3-Pyrroline containing arylacetamides: a novel series of remarkably selective kappa-agonists. Bioorg Med Chem Lett 12:2287-90 (2002) [PubMed]  Article 
Target
Name:
Kappa-type opioid receptor
Synonyms:
KOR-1 | Kappa Opioid Receptor | OPIATE Kappa | OPRK_RAT | Opioid receptor | Oprk1 | Ror-d
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42692.90
Organism:
Rattus norvegicus (rat)
Description:
P34975
Residue:
380
Sequence:
MESPIQIFRGEPGPTCAPSACLLPNSSSWFPNWAESDSNGSVGSEDQQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSAVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLASSVGISAIVLGGTKVREDVDVIECSLQFPDDEYSWWDLFMKICVFVFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITKLVLVVVAVFIICWTPIHIFILVEALGSTSHSTAVLSSYYFCIALGYTNSSLNPVLYAFLDENFKRCFRDFCFPIKMRMERQSTNRVRNTVQDPASMRDVGGMNKPV
  
Inhibitor
Name:
BDBM50116659
Synonyms:
2-(3,4-Dichloro-phenyl)-N-[(S)-1-(2,5-dihydro-pyrrol-1-ylmethyl)-2-methyl-propyl]-N-methyl-acetamide | CHEMBL75831
Type:
Small organic molecule
Emp. Form.:
C18H24Cl2N2O
Mol. Mass.:
355.302
SMILES:
CC(C)[C@@H](CN1CC=CC1)N(C)C(=O)Cc1ccc(Cl)c(Cl)c1 |c:7|
Structure:
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