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TargetAngiotensin II receptor
LigandBDBM50091105
Substrate/Competitorn/a
Meas. Tech.ChEMBL_36920
Ki>0.000100±n/a nM
Citation Murugesan, NTellew, JEGu, ZKunst, BLFadnis, LCornelius, LABaska, RAYang, YBeyer, SMMonshizadegan, HDickinson, KEPanchal, BValentine, MTChong, SMorrison, RACarlson, KEPowell, JRMoreland, SBarrish, JCKowala, MCMacor, JE Discovery of N-isoxazolyl biphenylsulfonamides as potent dual angiotensin II and endothelin A receptor antagonists. J Med Chem45:3829-35 (2002) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Angiotensin II receptor
Name:Angiotensin II receptor
Synonyms:AT1 | AT1AR | AT1BR | Angiotensin II AT1 | Angiotensin II receptor | Angiotensin II type 1b (AT-1b) receptor | Type-1 angiotensin II receptor (AT1)
Type:Protein
Mol. Mass.:41080.75
Organism:Homo sapiens (Human)
Description:P30556
Residue:359
Sequence:
MILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVC
AFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFK
IIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIAYFNNCLNPL
FYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSTKKPAPCFEVE
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50091105
NameBDBM50091105
Synonyms:4''-Oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide | 4'-Oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide | 4'-Oxazol-2-yl-biphenyl-2-sulfonicacid(3,4-dimethyl-isoxazol-5-yl)-amide | BMS-193884 | CHEMBL24461
TypeSmall organic molecule
Emp. Form.C20H17N3O4S
Mol. Mass.395.432
SMILESCc1noc(NS(=O)(=O)c2ccccc2-c2ccc(cc2)-c2ncco2)c1C
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a