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Target
Carboxypeptidase A1
Ligand
BDBM50121272
Substrate
n/a
Meas. Tech.
ChEMBL_45618 (CHEMBL655429)
Ki
650±n/a nM
Citation
 Park, JD; Kim, DH; Kim, SJ; Woo, JR; Ryu, SE Sulfamide-based inhibitors for carboxypeptidase A. Novel type transition state analogue inhibitors for zinc proteases. J Med Chem 45:5295-302 (2002) [PubMed]  Article 
Target
Name:
Carboxypeptidase A1
Synonyms:
CBPA1_BOVIN | CPA | CPA1 | Carboxypeptidase A | Carboxypeptidase A (CPA) | Carboxypeptidase A1 precursor
Type:
Enzyme
Mol. Mass.:
47073.90
Organism:
Bos taurus (bovine)
Description:
From Sigma-Aldrich Co.
Residue:
419
Sequence:
MQGLLILSVLLGAALGKEDFVGHQVLRITAADEAEVQTVKELEDLEHLQLDFWRGPGQPGSPIDVRVPFPSLQAVKVFLEAHGIRYRIMIEDVQSLLDEEQEQMFASQSRARSTNTFNYATYHTLDEIYDFMDLLVAEHPQLVSKLQIGRSYEGRPIYVLKFSTGGSNRPAIWIDLGIHSREWITQATGVWFAKKFTEDYGQDPSFTAILDSMDIFLEIVTNPDGFAFTHSQNRLWRKTRSVTSSSLCVGVDANRNWDAGFGKAGASSSPCSETYHGKYANSEVEVKSIVDFVKDHGNFKAFLSIHSYSQLLLYPYGYTTQSIPDKTELNQVAKSAVEALKSLYGTSYKYGSIITTIYQASGGSIDWSYNQGIKYSFTFELRDTGRYGFLLPASQIIPTAQETWLGVLTIMEHTLNNLY
  
Inhibitor
Name:
BDBM50121272
Synonyms:
(2S)-2-[(aminosulfonyl)amino]-3-phenylpropanoic acid | CHEMBL422668 | PHENYLALANINE-N-SULFONAMIDE
Type:
Small organic molecule
Emp. Form.:
C9H12N2O4S
Mol. Mass.:
244.268
SMILES:
NS(=O)(=O)N[C@@H](Cc1ccccc1)C(O)=O
Structure:
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