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Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50124717
Substrate
n/a
Meas. Tech.
ChEBML_157538
Ki
0.094000±n/a nM
Citation
 Kaltenbach, RF; Patel, M; Waltermire, RE; Harris, GD; Stone, BR; Klabe, RM; Garber, S; Bacheler, LT; Cordova, BC; Logue, K; Wright, MR; Erickson-Viitanen, S; Trainor, GL Synthesis, antiviral activity and pharmacokinetics of P1/P1' substituted 3-aminoindazole cyclic urea HIV protease inhibitors. Bioorg Med Chem Lett 13:605-8 (2003) [PubMed]  Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50124717
Synonyms:
(4R,5S,6S,7R)-1-(3-Amino-1H-indazol-5-ylmethyl)-3-butyl-4,7-bis-(4-ethyl-benzyl)-5,6-dihydroxy-[1,3]diazepan-2-one | CHEMBL349347
Type:
Small organic molecule
Emp. Form.:
C35H45N5O3
Mol. Mass.:
583.7635
SMILES:
CCCCN1[C@H](Cc2ccc(CC)cc2)[C@H](O)[C@@H](O)[C@@H](Cc2ccc(CC)cc2)N(Cc2ccc3[nH]nc(N)c3c2)C1=O
Structure:
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