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Target
Ecdysone receptor
Ligand
BDBM50128303
Substrate
n/a
Meas. Tech.
ChEBML_65456
EC50
5160.0±n/a nM
Citation
 Tice, CM; Hormann, RE; Thompson, CS; Friz, JL; Cavanaugh, CK; Saggers, JA Optimization of alpha-acylaminoketone ecdysone agonists for control of gene expression. Bioorg Med Chem Lett 13:1883-6 (2003) [PubMed]  Article 
Target
Name:
Ecdysone receptor
Synonyms:
20-hydroxy-ecdysone receptor | 20E receptor | ECR_BOMMO | EcR | EcRH | Ecdysteroid receptor | NR1H1 | Nuclear receptor subfamily 1 group H member 1
Type:
PROTEIN
Mol. Mass.:
68199.29
Organism:
Bombyx mori
Description:
ChEMBL_65456
Residue:
606
Sequence:
MRVENVDNVSFALNGRADEWCMSVETRLDSLVREKSEVKAYVGGCPSVITDAGAYDALFDMRRRWSNNGGFPLRMLEESSSEVTSSSALGLPPAMVMSPESLASPEYRALELWSYDDGITYNTAQSLLGACNMQQQQLQPQQPHPAPPTLPTMPLPMPPTTPKSENESMSSGREELSPASSINGCSADADARRQKKGPAPRQQEELCLVCGDRASGYHYNALTCEGCKGFFRRSVTKNAVYICKFGHACEMDMYMRRKCQECRLKKCLAVGMRPECVIQEPSKNKDRQRQKKDKGILLPVSTTTVEDHMPPIMQCDPPPPEAARIHEVVPRYLSEKLMEQNRQKNIPPLSANQKSLIARLVWYQEGYEQPSDEDLKRVTQTWQSDEEDEESDLPFRQITEMTILTVQLIVEFAKGLPGFSKISQSDQITLLKASSSEVMMLRVARRYDAASDSVLFANNKAYTRDNYRQGGMAYVIEDLLHFCRCMFAMGMDNVHFALLTAIVIFSDRPGLEQPSLVEEIQRYYLNTLRIYIINQNSASSRCAVIYGRILSVLTELRTLGTQNSNMCISLKLKNRKLPPFLEEIWDVAEVATTHPTVLPPTNPVVL
  
Inhibitor
Name:
BDBM50128303
Synonyms:
3-Methoxy-N-[1-(2-methoxy-benzoyl)-cyclopentyl]-2-methyl-benzamide | CHEMBL298593
Type:
Small organic molecule
Emp. Form.:
C22H25NO4
Mol. Mass.:
367.4382
SMILES:
COc1cccc(C(=O)NC2(CCCC2)C(=O)c2ccccc2OC)c1C
Structure:
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