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Target
Vasopressin V1a receptor
Ligand
BDBM50129472
Substrate
n/a
Meas. Tech.
ChEBML_214555
IC50
19±n/a nM
Citation
 Sum, FW; Dusza, J; Santos, ED; Grosu, G; Reich, M; Du, X; Albright, JD; Chan, P; Coupet, J; Ru, X; Mazandarani, H; Saunders, T Structure-activity study of novel tricyclic benzazepine arginine vasopressin antagonists. Bioorg Med Chem Lett 13:2195-8 (2003) [PubMed]  Article 
Target
Name:
Vasopressin V1a receptor
Synonyms:
Avpr1a | V1AR_RAT | VASOPRESSIN V1A | Vasopressin V1 receptor | Vasopressin V1a receptor | Vasopressin receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
47674.81
Organism:
RAT
Description:
VASOPRESSIN V1A AVPR1A RAT::P30560
Residue:
424
Sequence:
MSFPRGSQDRSVGNSSPWWPLTTEGSNGSQEAARLGEGDSPLGDVRNEELAKLEIAVLAVIFVVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQLCWDITYRFRGPDWLCRVVKHLQVFAMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIATSWVLSFILSTPQYFIFSVIEIEVNNGTKTQDCWATFIQPWGTRAYVTWMTSGVFVAPVVVLGTCYGFICYHIWRNIRGKTASSRHSKGDKGSGEAVGPFHKGLLVTPCVSSVKSISRAKIRTVKMTFVIVSAYILCWAPFFIVQMWSVWDENFIWTDSENPSITITALLASLNSCCNPWIYMFFSGHLLQDCVQSFPCCHSMAQKFAKDDSDSMSRRQTSYSNNRSPTNSTGMWKDSPKSSKSIRFIPVST
  
Inhibitor
Name:
BDBM50129472
Synonyms:
CHEMBL70949 | N-[4-(5,11-Dihydro-dibenzo[b,e][1,4]diazepine-10-carbonyl)-phenyl]-2-methyl-benzamide
Type:
Small organic molecule
Emp. Form.:
C28H23N3O2
Mol. Mass.:
433.5011
SMILES:
Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1Cc2ccccc2Nc2ccccc12
Structure:
Search PDB for entries with ligand similarity: