Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 5
Ligand
BDBM50133786
Substrate
n/a
Meas. Tech.
ChEBML_144129
Ki
1449±n/a nM
Citation
 Elliott, RL; Oliver, RM; LaFlamme, JA; Gillaspy, ML; Hammond, M; Hank, RF; Maurer, TS; Baker, DL; DaSilva-Jardine, PA; Stevenson, RW; Mack, CM; Cassella, JV Structure-activity relationship studies on 2-heteroaryl-4-arylimidazoles NPY5 receptor antagonists. Bioorg Med Chem Lett 13:3593-6 (2003) [PubMed]  Article 
Target
Name:
Neuropeptide Y receptor type 5
Synonyms:
NPY-Y5 | NPY-Y5 receptor | NPY5-R | NPY5R | NPY5R_HUMAN | NPYR5 | NPYY5 | Neuropeptide Y receptor type 5 | Neuropeptide Y receptor type 5 ( NPY Y5) | Y5 receptor
Type:
Enzyme
Mol. Mass.:
50746.64
Organism:
Homo sapiens (Human)
Description:
Q15761
Residue:
445
Sequence:
MDLELDEYYNKTLATENNTAATRNSDFPVWDDYKSSVDDLQYFLIGLYTFVSLLGFMGNLLILMALMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKVMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSLVELQETFGSALLSSRYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISCGLSNKENRLEENEMINLTLHPSKKSGPQVKLSGSHKWSYSFIKKHRRRYSKKTACVLPAPERPSQENHSRILPENFGSVRSQLSSSSKFIPGVPTCFEIKPEENSDVHELRVKRSVTRIKKRSRSVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCLNPILYGFLNNGIKADLVSLIHCLHM
  
Inhibitor
Name:
BDBM50133786
Synonyms:
2-(5-Phenyl-1H-imidazol-2-yl)-pyridine | CHEMBL325171
Type:
Small organic molecule
Emp. Form.:
C14H11N3
Mol. Mass.:
221.2572
SMILES:
c1[nH]c(nc1-c1ccccc1)-c1ccccn1
Structure:
Search PDB for entries with ligand similarity: