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Target
Alpha-galactosidase A
Ligand
BDBM50137351
Substrate
n/a
Meas. Tech.
ChEBML_34241
Ki
300000±n/a nM
Citation
 Kröger, L; Henkensmeier, D; Schäfer, A; Thiem, J Novel O-glycosyl amino acid mimetics as building blocks for O-glycopeptides act as inhibitors of galactosidases. Bioorg Med Chem Lett 14:73-5 (2003) [PubMed]  Article 
Target
Name:
Alpha-galactosidase A
Synonyms:
AGAL_HUMAN | Alpha-D-galactosidase A | Alpha-D-galactoside galactohydrolase | Alpha-galactosidase A | Alpha-glucosidase A (α-Gal A) | GLA | INN=Agalsidase | Melibiase
Type:
Protein
Mol. Mass.:
48760.21
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
429
Sequence:
MQLRNPELHLGCALALRFLALVSWDIPGARALDNGLARTPTMGWLHWERFMCNLDCQEEPDSCISEKLFMEMAELMVSEGWKDAGYEYLCIDDCWMAPQRDSEGRLQADPQRFPHGIRQLANYVHSKGLKLGIYADVGNKTCAGFPGSFGYYDIDAQTFADWGVDLLKFDGCYCDSLENLADGYKHMSLALNRTGRSIVYSCEWPLYMWPFQKPNYTEIRQYCNHWRNFADIDDSWKSIKSILDWTSFNQERIVDVAGPGGWNDPDMLVIGNFGLSWNQQVTQMALWAIMAAPLFMSNDLRHISPQAKALLQDKDVIAINQDPLGKQGYQLRQGDNFEVWERPLSGLAWAVAMINRQEIGGPRSYTIAVASLGKGVACNPACFITQLLPVKRKLGFYEWTSRLRSHINPTGTVLLQLENTMQMSLKDLL
  
Inhibitor
Name:
BDBM50137351
Synonyms:
2-(R)-Amino-3-(3,4,5,6-tetrahydroxy-tetrahydro-pyran-2-ylmethoxy)-butyric acid | CHEMBL3215440
Type:
Small organic molecule
Emp. Form.:
C10H19NO8
Mol. Mass.:
281.2598
SMILES:
C[C@@H](OC[C@H]1O[C@@H](O)[C@H](O)[C@H](O)[C@@H]1O)[C@H](N)C(O)=O
Structure:
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