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TargetMuscarinic acetylcholine receptor M2
LigandBDBM50142822
Substrate/Competitorn/a
Meas. Tech.ChEBML_139762
Ki 106±n/a nM
Citation Palani, ADugar, SClader, JWGreenlee, WJRuperto, VDuffy, RALachowicz, JE Isopropyl amide derivatives of potent and selective muscarinic M2 receptor antagonists. Bioorg Med Chem Lett14:1791-4 (2004) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Muscarinic acetylcholine receptor M2
Name:Muscarinic acetylcholine receptor M2 and M5
Synonyms:CHRM2 | Cholinergic, muscarinic M2 | RecName: Full=Muscarinic acetylcholine receptor M2
Type:GPCR
Mol. Mass.:51730.61
Organism:Homo sapiens (Human)
Description:P08172
Residue:466
Sequence:
MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNY
FLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFD
RYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQF
FSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRI
VKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDE
ITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNI
VARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNT
VWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
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  Blast E-value cutoff:
BDBM50142822
NameBDBM50142822
Synonyms:CHEMBL51982 | N-tert-Butyl-4-[1'-(2-methyl-benzoyl)-[1,4']bipiperidinyl-4-ylmethyl]-benzamide
TypeSmall organic molecule
Emp. Form.C30H41N3O2
Mol. Mass.475.6654
SMILESCc1ccccc1C(=O)N1CCC(CC1)N1CCC(Cc2ccc(cc2)C(=O)NC(C)(C)C)CC1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a