Reaction Details Report a problem with these data
Target
Delta-type opioid receptor
Ligand
BDBM50144250
Substrate
n/a
Meas. Tech.
ChEMBL_145487 (CHEMBL752130)
Ki
5.7±n/a nM
Citation
 Carson, JR; Coats, SJ; Codd, EE; Dax, SL; Lee, J; Martinez, RP; Neilson, LA; Pitis, PM; Zhang, SP N,N-dialkyl-4-[(8-azabicyclo[3.2.1]-oct-3-ylidene)phenylmethyl]benzamides, potent, selective delta opioid agonists. Bioorg Med Chem Lett 14:2109-12 (2004) [PubMed]  Article 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50144250
Synonyms:
CHEMBL63597 | N,N-Diethyl-4-{[(1S,5R)-8-methyl-8-aza-bicyclo[3.2.1]oct-(3Z)-ylidene]-phenyl-methyl}-benzamide
Type:
Small organic molecule
Emp. Form.:
C26H32N2O
Mol. Mass.:
388.5451
SMILES:
CCN(CC)C(=O)c1ccc(cc1)C(=C1\C[C@@H]2CC[C@H](C1)N2C)\c1ccccc1 |THB:22:21:14.15.20:17.18|
Structure:
Search PDB for entries with ligand similarity: