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Target
Dynamin-1
Ligand
BDBM50147565
Substrate
n/a
Meas. Tech.
ChEBML_60874
IC50
10190±n/a nM
Citation
 Hill, TA; Odell, LR; Quan, A; Abagyan, R; Ferguson, G; Robinson, PJ; McCluskey, A Long chain amines and long chain ammonium salts as novel inhibitors of dynamin GTPase activity. Bioorg Med Chem Lett 14:3275-8 (2004) [PubMed]  Article 
Target
Name:
Dynamin-1
Synonyms:
DNM | DNM1 | DYN1_HUMAN | Dynamin-1
Type:
PROTEIN
Mol. Mass.:
97411.67
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1458576
Residue:
864
Sequence:
MGNRGMEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLVLQLVNATTEYAEFLHCKGKKFTDFEEVRLEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANSDLANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIDGKKDITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQLTNHIRDTLPGLRNKLQSQLLSIEKEVEEYKNFRPDDPARKTKALLQMVQQFAVDFEKRIEGSGDQIDTYELSGGARINRIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDMAFETIVKKQVKKIREPCLKCVDMVISELISTVRQCTKKLQQYPRLREEMERIVTTHIREREGRTKEQVMLLIDIELAYMNTNHEDFIGFANAQQRSNQMNKKKTSGNQDEILVIRKGWLTINNIGIMKGGSKEYWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDYRQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVETIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSCGDQNTLMEESAEQAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPTPQRRAPAVPPARPGSRGPAPGPPPAGSALGGAPPVPSRPGASPDPFGPPPQVPSRPNRAPPGVPSRSGQASPSRPESPRPPFDL
  
Inhibitor
Name:
BDBM50147565
Synonyms:
CHEMBL110738 | Tributyl-hexadecyl-phosphonium; bromide
Type:
Small organic molecule
Emp. Form.:
C28H60P
Mol. Mass.:
427.7492
SMILES:
CCCCCCCCCCCCCCCC[P+](CCCC)(CCCC)CCCC
Structure:
Search PDB for entries with ligand similarity: