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Target
Fatty acid-binding protein, adipocyte
Ligand
BDBM50152881
Substrate
n/a
Meas. Tech.
ChEMBL_305926 (CHEMBL833473)
IC50
33000±n/a nM
Citation
 Ringom, R; Axen, E; Uppenberg, J; Lundbäck, T; Rondahl, L; Barf, T Substituted benzylamino-6-(trifluoromethyl)pyrimidin-4(1H)-ones: a novel class of selective human A-FABP inhibitors. Bioorg Med Chem Lett 14:4449-52 (2004) [PubMed]  Article 
Target
Name:
Fatty acid-binding protein, adipocyte
Synonyms:
A-FABP | AFABP | ALBP | Adipocyte lipid-binding protein | FABP4 | FABP4_HUMAN | Fatty acid binding protein adipocyte | Fatty acid-binding protein 4 | Fatty acid-binding protein 4 (FABP4)
Type:
Enzyme
Mol. Mass.:
14719.23
Organism:
Homo sapiens (Human)
Description:
P15090
Residue:
132
Sequence:
MCDAFVGTWKLVSSENFDDYMKEVGVGFATRKVAGMAKPNMIISVNGDVITIKSESTFKNTEISFILGQEFDEVTADDRKVKSTITLDGGVLVHVQKWDGKSTTIKRKREDDKLVVECVMKGVTSTRVYERA
  
Inhibitor
Name:
BDBM50152881
Synonyms:
2-(3-Chloro-benzylamino)-6-trifluoromethyl-pyrimidin-4-ol | CHEMBL363720
Type:
Small organic molecule
Emp. Form.:
C12H9ClF3N3O
Mol. Mass.:
303.668
SMILES:
FC(F)(F)c1cc(=O)[nH]c(NCc2cccc(Cl)c2)n1
Structure:
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